Elevated endogenous expression of the dominant negative basic helix-loop-helix protein ID1 correlates with significant centrosome abnormalities in human tumor cells

<p>Abstract</p> <p>Background</p> <p>ID proteins are dominant negative inhibitors of basic helix-loop-helix transcription factors that have multiple functions during development and cellular differentiation. Ectopic (over-)expression of ID1 extends the lifespan of prima...

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Bibliographic Details
Main Authors: Gutmann Anja, Mern Demissew S, Manthey Carolin, Zielinski Anne J, Herz Corinna, Lassmann Silke, Hasskarl Jens
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/11/2