Computational design of small interfering RNAs and small hairpin RNAs to silence mutated P53 gene expressions
RNA silencing is a novel gene regulatory mechanism that confines the transcript level by either preventing translation or by the initiation of particular RNA degradation. Small interfering RNAs are regularly represented as the exogenously made or viral inducers of RNAi. Such small RNAs have been use...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-01-01
|
Series: | Informatics in Medicine Unlocked |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352914818300443 |