Epigenetic condensates regulate chromatin activity and tumorigenesis

Alterations of epigenetic modulators are extensively associated with cancer, but their key molecular activities in cancer regulation are often unclear. We discovered that lysine demethylase 6A (KDM6A, also known as UTX) suppresses cancer by forming liquid-like condensates with lysine methyltransfera...

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Bibliographic Details
Main Authors: Bi Shi, Wei Li, Hao Jiang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-09-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2021.1997040