Improving Between-Group Effect Size for Multi-Site Functional Connectivity Data via Site-Wise De-Meaning

Background: Multi-site functional MRI (fMRI) databases are becoming increasingly prevalent in the study of neurodevelopmental and psychiatric disorders. However, multi-site databases are known to introduce site effects that may confound neurobiological and measures such as functional connectivity (F...

Full description

Bibliographic Details
Main Authors: Alexandra M. Reardon, Kaiming Li, Xiaoping P. Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Computational Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fncom.2021.762781/full