Immune responses to the enduring hypoxic response antigen Rv0188 are preferentially detected in Mycobacterium bovis infected cattle with low pathology.

The DosR regulon and the Enduring Hypoxic Response (EHR) define a group of M. tuberculosis genes that are specifically induced in bacilli exposed in vitro to conditions thought to mimic the environment encountered by Mycobacteria during latent infection. Although well described in humans, latent myc...

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Bibliographic Details
Main Authors: Gareth J Jones, Chris Pirson, Hannah P Gideon, Katalin A Wilkinson, David R Sherman, Robert J Wilkinson, R Glyn Hewinson, H Martin Vordermeier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3119702?pdf=render