The dynamic assembly of distinct RNA polymerase I complexes modulates rDNA transcription

The dynamic assembly of distinct RNA polymerase I complexes modulates rDNA transcription

Cell growth requires synthesis of ribosomal RNA by RNA polymerase I (Pol I). Binding of initiation factor Rrn3 activates Pol I, fostering recruitment to ribosomal DNA promoters. This fundamental process must be precisely regulated to satisfy cell needs at any time. We present in vivo evidence that,...

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Bibliographic Details
Main Authors: Eva Torreira, Jaime Alegrio Louro, Irene Pazos, Noelia González-Polo, David Gil-Carton, Ana Garcia Duran, Sébastien Tosi, Oriol Gallego, Olga Calvo, Carlos Fernández-Tornero
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-03-01
Series:eLife
Subjects:
growth control
ribosomal RNA synthesis
RNA polymerase I
Rrn3
transcriptional activation
Online Access:https://elifesciences.org/articles/20832

Internet

https://elifesciences.org/articles/20832

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