Ex-vivo drug screening of surgically resected glioma stem cells to replace murine avatars and provide personalise cancer therapy for glioblastoma patients [version 1; peer review: 2 approved]

With diminishing returns and high clinical failure rates from traditional preclinical and animal-based drug discovery strategies, more emphasis is being placed on alternative drug discovery platforms. Ex vivo approaches represent a departure from both more traditional preclinical animal-based models...

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Main Authors: Hannah Gagg, Greg Wells, Sarah J. Danson, Spencer J. Collis, Juha Rantala, Ola Rominiyi, Callum Jones, Thomas Helleday, Katie N. Myers, Connor McGarrity-Cottrell, Sophie T. Williams, Samantha Conroy
Format: Article
Language:English
Published: F1000 Research Ltd 2023-08-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/12-954/v1