Protein Disulfide Isomerase A3 Regulates Influenza Neuraminidase Activity and Influenza Burden in the Lung

Protein Disulfide Isomerase A3 Regulates Influenza Neuraminidase Activity and Influenza Burden in the Lung

Influenza (IAV) neuraminidase (NA) is a glycoprotein required for the viral exit from the cell. NA requires disulfide bonds for proper function. We have recently demonstrated that protein disulfide isomerase (PDI)A3 is required for oxidative folding of IAV hemagglutinin (HA), and viral propagation....

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Bibliographic Details
Main Authors: Nicolas Chamberlain, Mona Ruban, Zoe F. Mark, Sierra R. Bruno, Amit Kumar, Ravishankar Chandrasekaran, Dhemerson Souza De Lima, Danielle Antos, Emily M. Nakada, John F. Alcorn, Vikas Anathy
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
influenza
PDIA3
NA
disulfides
LOC14
Online Access:https://www.mdpi.com/1422-0067/23/3/1078

Internet

https://www.mdpi.com/1422-0067/23/3/1078

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