FilGAP regulates tumor growth in Glioma through the regulation of mTORC1 and mTORC2

Abstract The mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase that forms the two different protein complexes, known as mTORC1 and mTORC2. mTOR signaling is activated in a variety of tumors, including glioma that is one of the malignant brain tumors. FilGAP (ARHGAP24) is a...

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Váldodahkkit: Koji Tsutsumi, Ayumi Nohara, Taiki Tanaka, Moe Murano, Yurina Miyagaki, Yasutaka Ohta
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Nature Portfolio 2023-12-01
Ráidu:Scientific Reports
Liŋkkat:https://doi.org/10.1038/s41598-023-47892-1