Release of condensin from mitotic chromosomes requires the Ran-GTP gradient in the reorganized nucleus
After mitosis, nuclear reorganization occurs together with decondensation of mitotic chromosomes and reformation of the nuclear envelope, thereby restoring the Ran-GTP gradient between the nucleus and cytoplasm. The Ran-GTP gradient is dependent on Pim1/RCC1. Interestingly, a defect in Pim1/RCC1 in...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2017-11-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/6/11/1614 |