Release of condensin from mitotic chromosomes requires the Ran-GTP gradient in the reorganized nucleus

After mitosis, nuclear reorganization occurs together with decondensation of mitotic chromosomes and reformation of the nuclear envelope, thereby restoring the Ran-GTP gradient between the nucleus and cytoplasm. The Ran-GTP gradient is dependent on Pim1/RCC1. Interestingly, a defect in Pim1/RCC1 in...

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Bibliographic Details
Main Authors: Keita Aoki, Hironori Niki
Format: Article
Language:English
Published: The Company of Biologists 2017-11-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/6/11/1614