Inhibition of Thioredoxin Reductase by Santamarine Conferring Anticancer Effect in HeLa Cells

Inhibition of Thioredoxin Reductase by Santamarine Conferring Anticancer Effect in HeLa Cells

Natural products frequently have unique physiological activities and new action mechanisms due to their structural diversity and novelty, and are an important source for innovative drugs and lead compounds. We present herein that natural product santamarine targeted thioredoxin reductase (TrxR) to w...

Full description

Bibliographic Details
Main Authors: Junmin Zhang, Qianhe Xu, Hong-Ying Yang, Minghao Yang, Jianguo Fang, Kun Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
thioredoxin reductase
reactive oxygen species
santamarine
oxidative stress
apoptosis
natural product
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.710676/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.710676/full

Similar Items