Eukaryotic initiation factor 2 signaling behind neural invasion linked with lymphatic and vascular invasion in pancreatic cancer

Eukaryotic initiation factor 2 signaling behind neural invasion linked with lymphatic and vascular invasion in pancreatic cancer

Abstract Perineural invasion (PNI) is a typical poor prognostic factor in pancreatic ductal adenocarcinoma (PDAC). The mechanisms linking PNI to poor prognosis remain unclear. This study aimed to clarify what changes occurred alongside PNI in PDAC. A 128-patient cohort undergoing surgery for early-s...

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Bibliographic Details
Main Authors: Taiichi Wakiya, Keinosuke Ishido, Norihisa Kimura, Hayato Nagase, Tadashi Yoshizawa, Satoko Morohashi, Hiroaki Fujita, Taishu Kanda, Yota Tatara, Junji Saruwatari, Hiroshi Kijima, Kenichi Hakamada
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-00727-3

Internet

https://doi.org/10.1038/s41598-021-00727-3

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