Immunisation Using Novel DNA Vaccine Encoding Virus Membrane Fusion Complex and Chemokine Genes Shows High Protection from HSV-2

Immunisation Using Novel DNA Vaccine Encoding Virus Membrane Fusion Complex and Chemokine Genes Shows High Protection from HSV-2

Herpes simplex virus 1 and 2 infections cause high unmet disease burdens worldwide. Mainly HSV-2 causes persistent sexually transmitted disease, fatal neonatal disease and increased transmission of HIV/AIDS. Thus, there is an urgent requirement to develop effective vaccines. We developed nucleic aci...

Full description

Bibliographic Details
Main Authors: Ursula A. Gompels, Fernando J. Bravo, Sean Briggs, Shima Ameri, Rhonda D. Cardin, David I. Bernstein
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Viruses
Subjects:
DNA vaccine
HSV-2 vaccine
cell fusion
chemokine
virus latency
neutralising antibodies
Online Access:https://www.mdpi.com/1999-4915/14/11/2317

Internet

https://www.mdpi.com/1999-4915/14/11/2317

Similar Items