Ca2+ pushes and pulls energetics to maintain ATP balance in atrial cells: computational insights

To maintain atrial function, ATP supply-to-demand matching must be tightly controlled. Ca2+ can modulate both energy consumption and production. In light of evidence suggesting that Ca2+ affects energetics through “push” (activating metabolite flux and enzymes in the Krebs cycle to push the redox fl...

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Bibliographic Details
Main Authors: Noam Keidar, Noa Kirschner Peretz, Yael Yaniv
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1231259/full