Ca2+ pushes and pulls energetics to maintain ATP balance in atrial cells: computational insights
To maintain atrial function, ATP supply-to-demand matching must be tightly controlled. Ca2+ can modulate both energy consumption and production. In light of evidence suggesting that Ca2+ affects energetics through “push” (activating metabolite flux and enzymes in the Krebs cycle to push the redox fl...
Main Authors: | Noam Keidar, Noa Kirschner Peretz, Yael Yaniv |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-07-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2023.1231259/full |
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