Gut microbes exacerbate systemic inflammation and behavior disorders in neurologic disease CADASIL

Abstract Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a cerebral small vessel disease that carries mutations in NOTCH3. The clinical manifestations are influenced by genetic and environmental factors that may include gut microbiom...

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Bibliographic Details
Main Authors: Sheng Liu, Xuejiao Men, Yang Guo, Wei Cai, Ruizhen Wu, Rongsui Gao, Weicong Zhong, Huating Guo, Hengfang Ruan, Shuli Chou, Junrui Mai, Suning Ping, Chao Jiang, Hongwei Zhou, Xiangyu Mou, Wenjing Zhao, Zhengqi Lu
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Microbiome
Subjects:
Online Access:https://doi.org/10.1186/s40168-023-01638-3