Glycemic Dysregulations Are Associated With Worsening Cognitive Function in Older Participants at High Risk of Cardiovascular Disease: Two-Year Follow-up in the PREDIMED-Plus Study

IntroductionType 2 diabetes has been linked to greater cognitive decline, but other glycemic parameters such as prediabetes, diabetes control and treatment, and HOMA-IR and HbA1c diabetes-related biomarkers have shown inconsistent results. Furthermore, there is limited research assessing these relat...

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Main Authors: Carlos Gómez-Martínez, Nancy Babio, Jordi Júlvez, Nerea Becerra-Tomás, Miguel Á. Martínez-González, Dolores Corella, Olga Castañer, Dora Romaguera, Jesús Vioque, Ángel M. Alonso-Gómez, Julia Wärnberg, José A. Martínez, Luís Serra-Majem, Ramón Estruch, Francisco J. Tinahones, José Lapetra, Xavier Pintó, Josep A. Tur, José López-Miranda, Aurora Bueno-Cavanillas, José J. Gaforio, Pilar Matía-Martín, Lidia Daimiel, Vicente Martín-Sánchez, Josep Vidal, Clotilde Vázquez, Emilio Ros, Søren Dalsgaard, Carmen Sayón-Orea, José V. Sorlí, Rafael de la Torre, Itziar Abete, Lucas Tojal-Sierra, Francisco J. Barón-López, Noelia Fernández-Brufal, Jadwiga Konieczna, Antonio García-Ríos, Emilio Sacanella, M. Rosa Bernal-López, José M. Santos-Lozano, Cristina Razquin, Andrea Alvarez-Sala, Albert Goday, M. Angeles Zulet, Jessica Vaquero-Luna, Javier Diez-Espino, Aida Cuenca-Royo, Fernando Fernández-Aranda, Mònica Bulló, Jordi Salas-Salvadó
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Endocrinology
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Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.754347/full