Chemical similarity and biological activities
"Similar molecules exert similar biological activities". Since long, medicinal chemists use this concept to modify the structures of biologically active compounds. Bioisosteric replacements of atoms and groups pave the way from various lead structures to therapeutically useful enzyme inhib...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
2002-01-01
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| Series: | Journal of the Brazilian Chemical Society |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532002000600002 |