Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats.

Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats.

Matriptase-2 (TMPRSS6) is an important negative regulator of hepcidin expression; however, the effects of iron overload or accelerated erythropoiesis on liver TMPRSS6 protein content in vivo are largely unknown. We determined TMPRSS6 protein content in plasma membrane-enriched fractions of liver hom...

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Bibliographic Details
Main Authors: Jana Frýdlová, Petr Přikryl, Jaroslav Truksa, Lucas L Falke, Xin Du, Iuliia Gurieva, Martin Vokurka, Jan Krijt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4742081?pdf=render

Internet

http://europepmc.org/articles/PMC4742081?pdf=render

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