The drug-resistance to gefitinib in PTEN low expression cancer cells is reversed by irradiation in vitro

<p>Abstract</p> <p>Background</p> <p>Despite of the recent success of EGFR inhibitory agents, the primary drug-resistant becomes a major challenge for EGFR inhibitor therapies. PTEN gene is an important positive regulatory factor for response to EGFR inhibitor therapy....

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Bibliographic Details
Main Authors: Zhao Lu-Jun, Yuan Zhi-Yong, Wang Jun, Zhuang Hong-Qing, Wang Ping, Wang Chang-Li
Format: Article
Language:English
Published: BMC 2009-09-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/28/1/123