The drug-resistance to gefitinib in PTEN low expression cancer cells is reversed by irradiation in vitro
<p>Abstract</p> <p>Background</p> <p>Despite of the recent success of EGFR inhibitory agents, the primary drug-resistant becomes a major challenge for EGFR inhibitor therapies. PTEN gene is an important positive regulatory factor for response to EGFR inhibitor therapy....
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-09-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Online Access: | http://www.jeccr.com/content/28/1/123 |