The aldehyde hypothesis: metabolic intermediates as antimicrobial effectors

There are many reactive intermediates found in metabolic pathways. Could these potentially toxic molecules be exploited for an organism's benefit? We propose that during certain microbial infections, the production of inherently reactive aldehydes by an infected host is a previously unappreciat...

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Bibliographic Details
Main Authors: K. Heran Darwin, Sarah A. Stanley
Format: Article
Language:English
Published: The Royal Society 2022-04-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.220010