Evolutionary Invariant of the Structure of DNA Double Helix in RNAP II Core Promoters

Eukaryotic and archaeal RNA polymerase II (POL II) machinery is highly conserved, regardless of the extreme changes in promoter sequences in different organisms. The goal of our work is to find the cause of this conservatism. The representative sets of aligned promoter sequences of fifteen organisms...

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Bibliographic Details
Main Authors: Anastasia V. Melikhova, Anastasia A. Anashkina, Irina A. Il’icheva
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/18/10873