Non-Invasive Monitoring of Corticosterone Levels in Mouse Urine with Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry

An innovative method for the quantification of corticosterone in the urine of C57BL/6J mice by liquid chromatography-electrospray ionization-tandem mass spectrometry was developed. Unconjugated and glucuronidated corticosterone was detected in the urine samples using enzymatic hydrolysis following l...

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Bibliographic Details
Main Authors: Laura Howe-Wittek, Paul Kroschk, Kai Nieschalke, Harshadrai M. Rawel, Stephanie Krämer, Jens Raila
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/22/5399