Benzisothiazolinone: Pharmacokinetics, Tissue Distribution, and Mass Balance Studies in Rats

Benzisothiazolinone: Pharmacokinetics, Tissue Distribution, and Mass Balance Studies in Rats

Humans are continuously exposed to benzisothiazolinone (BIT), which is used as a preservative, through multiple routes. BIT is known to be a sensitizer; in particular, dermal contact or aerosol inhalation could affect the local toxicity. In this study, we evaluated the pharmacokinetic properties of...

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Bibliographic Details
Main Authors: Seong Jun Jo, Soo Hyeon Bae, Zhouchi Huang, Sangyoung Lee, Chae Bin Lee, Soon Uk Chae, Jung Bae Park, Mihye Kwon, Hye Kyung Chung, Soo Kyung Bae
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Metabolites
Subjects:
benzisothiazolinone
various routes of exposure
pharmacokinetics
tissue distribution
mass balance
Online Access:https://www.mdpi.com/2218-1989/13/5/584

Internet

https://www.mdpi.com/2218-1989/13/5/584

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