Attenuation of dopamine-modulated prefrontal value signals underlies probabilistic reward learning deficits in old age

Probabilistic reward learning is characterised by individual differences that become acute in aging. This may be due to age-related dopamine (DA) decline affecting neural processing in striatum, prefrontal cortex, or both. We examined this by administering a probabilistic reward learning task to you...

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Bibliographic Details
Main Authors: Lieke de Boer, Jan Axelsson, Katrine Riklund, Lars Nyberg, Peter Dayan, Lars Bäckman, Marc Guitart-Masip
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/26424