A systems serology approach to the investigation of infection-induced antibody responses and protection in trachoma

A systems serology approach to the investigation of infection-induced antibody responses and protection in trachoma

BackgroundOcular infections with Chlamydia trachomatis serovars A–C cause the neglected tropical disease trachoma. As infection does not confer complete immunity, repeated infections are common, leading to long-term sequelae such as scarring and blindness. Here, we apply a systems serology approach...

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Bibliographic Details
Main Authors: Amber Barton, Ida Rosenkrands, Harry Pickering, Nkoyo Faal, Anna Harte, Hassan Joof, Pateh Makalo, Manon Ragonnet, Anja Weinreich Olsen, Robin L. Bailey, David C. W. Mabey, Frank Follmann, Jes Dietrich, Martin J. Holland
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
trachoma
Chlamydia trachomatis
antibody
systems serology
IgG
humoral immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178741/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178741/full

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