Variation in Host Resistance to Blastomyces dermatitidis: Potential Use of Genetic Reference Panels and Advances in Immunophenotyping of Diverse Mouse Strains

Variation in Host Resistance to Blastomyces dermatitidis: Potential Use of Genetic Reference Panels and Advances in Immunophenotyping of Diverse Mouse Strains

ABSTRACT Host genetic determinants that underpin variation in susceptibility to systemic fungal infection are poorly understood. Genes responsible for complex traits can be identified by correlating variation in phenotype with allele in founder strains of wild mice with known genetic variation, asse...

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Bibliographic Details
Main Authors: Elaine M. Kohn, Cleison Taira, Hanah Dobson, Lucas Dos Santos Dias, Uju Okaa, Darin L. Wiesner, Marcel Wüthrich, Bruce S. Klein
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mBio
Subjects:
fungi
immunity
resistance
mice
blastomycosis
adaptive immunity
Online Access:https://journals.asm.org/doi/10.1128/mbio.03400-21

Internet

https://journals.asm.org/doi/10.1128/mbio.03400-21

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