Macrofilaricidal effects of chloroquine on adult Onchocerca volvulus by local infiltration of palpable onchocercal nodules

The macrofilaricidal effects of local infiltration of high concentrations of chloroquine into the capsule of onchocercal nodules on adult worms of Onchocerca volvulus was determined. Six weeks post infiltration, histological examination of single nodules showed all adult worms to be dead. With nodul...

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Bibliographic Details
Main Authors: Ronald H. Guderian, Mariela Anselmi, Philip J. Cooper, Martha E. Chico
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 1997-12-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821997000600005&tlng=en