Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition
Abstract Background Parkinson’s disease (PD) is a neurodegenerative disorder that is characterized by the presence of proteinaceous alpha-synuclein (α-syn) inclusions (Lewy bodies), markers of neuroinflammation and the progressive loss of nigrostriatal dopamine (DA) neurons. These pathological featu...
| Main Authors: | , , , , , , , , |
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| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
BMC
2024-04-01
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| סדרה: | Journal of Neuroinflammation |
| נושאים: | |
| גישה מקוונת: | https://doi.org/10.1186/s12974-024-03108-5 |