Prostaglandin E2 (PGE2) and Roflumilast Involvement in IPF Progression
The ECM propagates processes in idiopathic pulmonary fibrosis (IPF), leading to progressive lung scarring. We established an IPF-conditioned matrix (IPF-CM) system as a platform for testing drug candidates. Here, we tested the involvement of a PGE2 and PDE4 inhibitor, Roflumilast, in the IPF-CM syst...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-08-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/15/12393 |