PI3K pathway mutation predicts an activated immune microenvironment and better immunotherapeutic efficacy in head and neck squamous cell carcinoma

PI3K pathway mutation predicts an activated immune microenvironment and better immunotherapeutic efficacy in head and neck squamous cell carcinoma

Abstract Background PI3K pathway is the most frequently mutated pathway in head and neck squamous cell carcinoma (HNSC), which plays a crucial role in tumorigenesis and progression. In the present study, we aimed to investigate the role of PI3K pathway mutation in clinical prognosis prediction and t...

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Bibliographic Details
Main Authors: Libo Wang, Kejun Chen, Siyuan Weng, Hui Xu, Yuqing Ren, Quan Cheng, Peng Luo, Jian Zhang, Zaoqu Liu, Xinwei Han
Format: Article
Language:English
Published: BMC 2023-03-01
Series:World Journal of Surgical Oncology
Subjects:
Head and neck squamous cell carcinoma
PI3K pathway mutation
Immunotherapy
Immune environment
Survival
Online Access:https://doi.org/10.1186/s12957-023-02938-6

Internet

https://doi.org/10.1186/s12957-023-02938-6

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