Luteolin alleviates methionine–choline-deficient diet-induced non-alcoholic steatohepatitis by modulating host serum metabolome and gut microbiome

Luteolin alleviates methionine–choline-deficient diet-induced non-alcoholic steatohepatitis by modulating host serum metabolome and gut microbiome

Background and purposePrevious studies have indicated the protective effects of luteolin against non-alcoholic steatohepatitis (NASH), but the definite underlying mechanism still remains unclear. This study aimed to explore the metabolomic and metagenomic signatures of NASH with luteolin supplementa...

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Bibliographic Details
Main Authors: Wei Guo, Lianxiang Luo, Yan Meng, Wen Chen, Lixiu Yu, Cong Zhang, Zhenpeng Qiu, Peng Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Nutrition
Subjects:
luteolin
non-alcoholic steatohepatitis
metabolomics
gut microbiota
thiamine
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.936237/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.936237/full

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