Chromatin Accessibility and Transcriptional Differences in Human Stem Cell-Derived Early-Stage Retinal Organoids

Chromatin Accessibility and Transcriptional Differences in Human Stem Cell-Derived Early-Stage Retinal Organoids

Retinogenesis involves the specification of retinal cell types during early vertebrate development. While model organisms have been critical for determining the role of dynamic chromatin and cell-type specific transcriptional networks during this process, an enhanced understanding of the developing...

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Bibliographic Details
Main Authors: Melissa K. Jones, Devansh Agarwal, Kevin W. Mazo, Manan Chopra, Shawna L. Jurlina, Nicholas Dash, Qianlan Xu, Anna R. Ogata, Melissa Chow, Alex D. Hill, Netra K. Kambli, Guorong Xu, Roman Sasik, Amanda Birmingham, Kathleen M. Fisch, Robert N. Weinreb, Ray A. Enke, Dorota Skowronska-Krawczyk, Karl J. Wahlin
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
CRISPR
organoids
retina
chromatin
transcription
gene-editing
Online Access:https://www.mdpi.com/2073-4409/11/21/3412

Internet

https://www.mdpi.com/2073-4409/11/21/3412

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