Striatonigral distribution of a fluorescent reporter following intracerebral delivery of genome editors

Introduction: Targeted gene editing is proposed as a therapeutic approach for numerous disorders, including neurological diseases. As the brain is organized into neural networks, it is critical to understand how anatomically connected structures are affected by genome editing. For example, neurons i...

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Bibliographic Details
Main Authors: Samuel S. Neuman, Jeanette M. Metzger, Viktoriya Bondarenko, Yuyuan Wang, Jesi Felton, Jon E. Levine, Krishanu Saha, Shaoqin Gong, Marina E. Emborg
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1237613/full