PopTradeOff: A database for exploring population-specificity of adaptive evolution, disease susceptibility, and drug responsiveness

The influence of adaptive evolution on disease susceptibility has drawn attention; however, the extent of the influence, whether favored mutations also influence drug responses, and whether the associations between the three are population-specific remain unknown. Using a reported deep learning netw...

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Bibliographic Details
Main Authors: Ji Tang, Huanlin Zhang, Hai Zhang, Hao Zhu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023002210