Nerve Growth Factor Pathobiology During the Progression of Alzheimer’s Disease

Nerve Growth Factor Pathobiology During the Progression of Alzheimer’s Disease

The current review summarizes the pathobiology of nerve growth factor (NGF) and its cognate receptors during the progression of Alzheimer’s disease (AD). Both transcript and protein data indicate that cholinotrophic neuronal dysfunction is related to an imbalance between TrkA-mediated survival signa...

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Bibliographic Details
Main Authors: Elliott J. Mufson, Scott E. Counts, Stephen D. Ginsberg, Laura Mahady, Sylvia E. Perez, Stephen M. Massa, Frank M. Longo, Milos D. Ikonomovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer
nerve growth factor
mild cognitive impairment
epigenetics
neurotrophin receptors
biomarker
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00533/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.00533/full

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