Global methylation patterns in idiopathic pulmonary fibrosis.

BACKGROUND:Idiopathic Pulmonary Fibrosis (IPF) is characterized by profound changes in the lung phenotype including excessive extracellular matrix deposition, myofibroblast foci, alveolar epithelial cell hyperplasia and extensive remodeling. The role of epigenetic changes in determining the lung phe...

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Bibliographic Details
Main Authors: Einat I Rabinovich, Maria G Kapetanaki, Israel Steinfeld, Kevin F Gibson, Kusum V Pandit, Guoying Yu, Zohar Yakhini, Naftali Kaminski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3323629?pdf=render