Role of the transcription factor Fli-1 on the CXCL10/CXCR3 Axis*

Role of the transcription factor Fli-1 on the CXCL10/CXCR3 Axis*

The transcription factor Fli-1, a member of the ETS family of transcription factors, is implicated in the pathogenesis of lupus disease. Reduced Fli-1 expression in lupus mice leads to decreased renal Cxcl10 mRNA levels and renal infiltrating CXCR3+ T cells that parallels reduced renal inflammatory...

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Bibliographic Details
Main Authors: Xuan Wang, Mara Lennard Richard, Tomika S. Caldwell, Kamala Sundararaj, Shuzo Sato, Tamara K. Nowling, Xian K. Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
CXCL10
CXCR3
chemokine
friend leukemia virus integration 1 transcription factor
inflammation
lupus nephritis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1219279/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1219279/full

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