Synthesis of an Anti-CD7 Recombinant Immunotoxin Based on PE24 in CHO and <i>E. coli</i> Cell-Free Systems

Recombinant immunotoxins (RITs) are an effective class of agents for targeted therapy in cancer treatment. In this article, we demonstrate the straight-forward production and testing of an anti-CD7 RIT based on PE24 in a prokaryotic and a eukaryotic cell-free system. The prokaryotic cell-free system...

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Bibliographic Details
Main Authors: Simon K. Krebs, Marlitt Stech, Felix Jorde, Nathanaël Rakotoarinoro, Franziska Ramm, Sophie Marinoff, Sven Bahrke, Antje Danielczyk, Doreen A. Wüstenhagen, Stefan Kubick
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/22/13697