Monitoring SARS-CoV-2 genetic variability: A post-market surveillance workflow for combined bioinformatic and laboratory evaluation of commercial RT-PCR assay performance.

<h4>Objective</h4>The speed at which Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is mutating has made it necessary to frequently assess how these genomic changes impact the performance of diagnostic real-time polymerase chain reaction (RT-PCR) assays. Herein, we describe...

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Bibliographic Details
Main Authors: Barbara Kosińska-Selbi, Justyna Kowalczyk, Jagoda Pierscińska, Jarosław Wełeszczuk, Luis Peñarrubia, Benjamin Turner, Josep Pareja, Roberto Porco, Rubi Diaz-Hernandez, Martí Juanola-Falgarona, Melisa Rey, Davide Manissero, Anna Blacha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0294271&type=printable