Effects of flora deficiency on the structure and function of the large intestine

Summary: The significant anatomical changes in large intestine of germ-free (GF) mice provide excellent material for understanding microbe-host crosstalk. We observed significant differences of GF mice in anatomical and physiological involving in enlarged cecum, thinned mucosal layer and enriched wa...

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Bibliographic Details
Main Authors: Tailiang Chai, Juan Shen, Yifei Sheng, Yufen Huang, Weiming Liang, Zhao Zhang, Ruizhen Zhao, Haitao Shang, Wei Cheng, Hang Zhang, Xueting Chen, Xiang Huang, Yin Zhang, Jiazhe Liu, Huanjie Yang, Linying Wang, Shanshan Pan, Yang Chen, Lijuan Han, Qinwei Qiu, Aibo Gao, Hong Wei, Xiaodong Fang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224001627