A mathematical model of in vitro hepatocellular cholesterol and lipoprotein metabolism for hyperlipidemia therapy

A mathematical model of in vitro hepatocellular cholesterol and lipoprotein metabolism for hyperlipidemia therapy

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Cardiovascular diseases associated with high cholesterol (hypercholesterolemia) and low-density lipoproteins (LDL) levels are significant contributors to total mortality in developing and developed countries. Mathematical modeling of LDL metabolism is an important step in the development of drugs fo...

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Bibliographic Details
Main Authors: Yuri Efremov, Anastasia Ermolaeva, Georgiy Vladimirov, Susanna Gordleeva, Andrey Svistunov, Alexey Zaikin, Peter Timashev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165868/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165868/?tool=EBI

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