Clinical consequences of a genetic predisposition toward higher benign prostate-specific antigen levelsResearch in context

Clinical consequences of a genetic predisposition toward higher benign prostate-specific antigen levelsResearch in context

Summary: Background: Prostate-specific antigen (PSA) levels are influenced by genetic variation unrelated to prostate cancer risk. Whether a genetic predisposition to a higher PSA level predisposes to a diagnostic work-up for prostate cancer is not known. Methods: Participants were 3110 men of Afri...

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Bibliographic Details
Main Authors: Mingjian Shi, John P. Shelley, Kerry R. Schaffer, Jeffrey J. Tosoian, Minoo Bagheri, John S. Witte, Linda Kachuri, Jonathan D. Mosley
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:EBioMedicine
Subjects:
Prostate specific antigen (PSA)
Polygenic score (PGS)
Prostate cancer
Associations
Cox proportional hazards regression
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423004048

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http://www.sciencedirect.com/science/article/pii/S2352396423004048

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