Orofacial Malformations in the Rat Foetuses Induced by Hypervitaminosis A
Single oral administration of 100,000 IU of vitamin A palmitate in oil to pregnant wistar rats on 8th, 9th or 10th day of gestation resulted in malformations of the tongue, jaw; lower lip and palate in 82%, live-born foetuses. The frequency and severity of defects were most marked in the group treat...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Thieme Medical Publishers, Inc.
1973-12-01
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Series: | Indian Journal of Plastic Surgery |
Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778249 |