Orofacial Malformations in the Rat Foetuses Induced by Hypervitaminosis A

Single oral administration of 100,000 IU of vitamin A palmitate in oil to pregnant wistar rats on 8th, 9th or 10th day of gestation resulted in malformations of the tongue, jaw; lower lip and palate in 82%, live-born foetuses. The frequency and severity of defects were most marked in the group treat...

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Bibliographic Details
Main Authors: Shamer Singh, Gurpreet Singh
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 1973-12-01
Series:Indian Journal of Plastic Surgery
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778249