Dexmedetomidine protects against oxygen-glucose deprivation/reoxygenation injury-induced apoptosis via the p38 MAPK/ERK signalling pathway

Objective To investigate the protective effects of dexmedetomidine (DEX) in oxygen-glucose deprivation/reoxygenation (OGD/R) injury, which is involved in a number of ischaemic diseases. Methods An in vitro OGD/R injury model was generated using mouse Neuro 2A neuroblastoma (N2A) cells. Different con...

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Bibliographic Details
Main Authors: Ke Wang, Yuekun Zhu
Format: Article
Language:English
Published: SAGE Publishing 2018-02-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060517734460