In Mitochondria β-Actin Regulates mtDNA Transcription and Is Required for Mitochondrial Quality Control
Summary: In eukaryotic cells, actin regulates both cytoplasmic and nuclear functions. However, whether actin-based structures are present in the mitochondria and are involved in mitochondrial functions has not been investigated. Here, using wild-type β-actin +/+ and knockout (KO) β-actin −/− mouse e...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-05-01
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Series: | iScience |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004218300531 |