Microcystin-LR accelerates follicular atresia in mice via JNK-mediated adherent junction damage of ovarian granulosa cells

Microcystin-LR accelerates follicular atresia in mice via JNK-mediated adherent junction damage of ovarian granulosa cells

Microcystin-LR (MC-LR), one of aquatic environmental contaminants with reproductive toxicity produced by cyanobacterial blooms, but its toxic effects and mechanisms on the ovary are not fully understood. Here, proteomic techniques and molecular biology experiments were performed to study the potenti...

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Bibliographic Details
Main Authors: Xingde Du, Yu Fu, Zhihui Tian, Haohao Liu, Hongxia Xin, Xiaoli Fu, Fufang Wang, Huizhen Zhang, Xin Zeng
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Microcystin-leucine arginine
Proteomics
Adherent junction
C-Jun N-terminal kinase
Follicular atresia
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323000969

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http://www.sciencedirect.com/science/article/pii/S0147651323000969

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