Combined effects of 5-Fluorouracil, Folinic acid and Oxaliplatin on the expression of carcinoembryonic antigen in human colon cancer cells: pharmacological basis to develop an active antitumor immunochemotherapy

<p>Abstract</p> <p>Background</p> <p>Five-fluorouracil (FU), mainly associated with leucovorin (L), plays an essential role in chemotherapy of colorectal carcinoma. Moreover, FU ± L has been found to increase the expression of tumor-associated carcinoembryonic antigen (...

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Bibliographic Details
Main Authors: De Vecchis Liana, Correale Pierpaolo, De Rossi Alessia, Massara Maria C, Turriziani Mario, Prete Salvatore P, Torino Francesco, Bonmassar Laura, Aquino Angelo
Format: Article
Language:English
Published: BMC 2008-05-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/27/1/5