Genomic variants in the FTO gene are associated with sporadic amyotrophic lateral sclerosis in Greek patients

Genomic variants in the FTO gene are associated with sporadic amyotrophic lateral sclerosis in Greek patients

Abstract Background Amyotrophic lateral sclerosis (ALS) is a devastating disease whose complex pathology has been associated with a strong genetic component in the context of both familial and sporadic disease. Herein, we adopted a next-generation sequencing approach to Greek patients suffering from...

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Main Authors: Konstantinos Mitropoulos, Eleni Merkouri Papadima, Georgia Xiromerisiou, Angeliki Balasopoulou, Kyriaki Charalampidou, Vasiliki Galani, Krystallia-Vassiliki Zafeiri, Efthymios Dardiotis, Styliani Ralli, Georgia Deretzi, Anne John, Kyriaki Kydonopoulou, Elpida Papadopoulou, Alba di Pardo, Fulya Akcimen, Annalisa Loizedda, Valerija Dobričić, Ivana Novaković, Vladimir S. Kostić, Clint Mizzi, Brock A. Peters, Nazli Basak, Sandro Orrù, Evangelos Kiskinis, David N. Cooper, Spyridon Gerou, Radoje Drmanac, Marina Bartsakoulia, Evangelia-Eirini Tsermpini, Georgios M. Hadjigeorgiou, Bassam R. Ali, Theodora Katsila, George P. Patrinos
פורמט: Article
שפה:English
יצא לאור: BMC 2017-12-01
סדרה:Human Genomics
נושאים:
Sporadic amyotrophic lateral sclerosis
FTO gene
Genomic variants
Whole-genome sequencing
Founder population
גישה מקוונת:http://link.springer.com/article/10.1186/s40246-017-0126-2

אינטרנט

http://link.springer.com/article/10.1186/s40246-017-0126-2

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