Murine Models of Acute Myeloid Leukemia

Murine Models of Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a phenotypically and genetically heterogeneous hematologic malignancy. Extensive sequencing efforts have mapped the genomic landscape of adult and pediatric AML revealing a number of biologically and prognostically relevant driver lesions. Beyond identifying recurrent...

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Bibliographic Details
Main Authors: Kristen J. Kurtz, Shannon E. Conneely, Madeleine O’Keefe, Katharina Wohlan, Rachel E. Rau
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
acute myeliod leukemia
AML
transgenic mouse
genetically engineered mice (GEM)
core binding factor acute myeliod leukemia
KMT2a (MLL) rearrangements
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.854973/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.854973/full

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